What is Sildigra 100?
Sildigra 100 is a tool for effective treatment of erectile dysfunction in men. The active agent of the generic is sildenafil 100 mg — the same substance and in the same dosage as in the drug Viagra.
Viagra is considered one of the most profitable medicines that have ever been sold in the history of mankind. Historically, sildenafil was one of the earliest monopolists in its field of application and until recently the only selective phosphodiesterase-5 (PDE-5) inhibitor. Naturally, and it was quite expected that after the expiration of the patent for the production of sildenafil, it will be manufactured by Indian manufacturers and sold under their own brand in a bright, typical for Viagra tablets style. What actually happened — Sildigra is a product of the Indian pharmaceutical industry, which has grown on the Foundation of the drug Viagra.
The action of the drug Sildigra 100 is based on the relaxation of smooth muscles that cover our blood vessels in the cavernous body of the penis, which actually leads to an increase in the lumen of the vessels and the appearance of an erection.
Some brands of generic sildenafil (e.g. Revatio) may improve physical condition and exercise tolerance in patients with pulmonary arterial hypertension.
Main characteristics of the generic Sildigra 100 trade name Sildigra 100
Production of RSM (India)
Pharmacological affiliation of the Drug for the elimination of erectile dysfunction
Composition Sildigra 100 sildenafil 100 mg
Inactive substances: Cellulose, hyprolose, lactose, iron oxide, Opadry blue, croscarmellose
Dosages are 50-100 mg per day. The maximum daily dose is 100 mg of sildenafil
Features of use Take on an unsatisfied stomach, 40-60 minutes before sexual intercourse
Package blister of 10 tablets
Storage 3 years
Dosage and administration of Sildigra 100
Sildigra 100 is taken orally (through the mouth). The accepted therapeutic dose of sildenafil can range from 25 to 100 mg, which is equivalent to 1/4-1 tablet of Sildigra 100. The recommended initial dosage is 50 mg of sildenafil, which is equal to half of The sildigra-100 tablet. Drugs based on sildenafil can be taken between 1-4 hours before sexual intercourse and no more than once a day. Elderly patients over 65 years of age and without contraindications can take sildenafil in the same dosages.
Contraindications
You should refrain from using Sildigra 100 if:
there is an Allergy to auxiliary agents means or directly to sildenafil;
sexual contact is contraindicated for health reasons;
use medications to relieve the patient’s condition in arterial pulmonary hypertension, such as riociguat (Adempas);
there are heart diseases, lesions of the coronary arteries of the heart or heart rhythm problems;
use medical nitrates to treat heart chest pain and heart disease-nitroglycerin, isosorbide dinitrate, or isosorbide Mononitrate. Nitrates are also found in some recreational drugs, such as “poppers” (amyl nitrite, butyl nitrite, and others);
retinitis pigmentosa;
peptic ulcer diseases of the 12 duodenum and stomach;
uncontrolled hypertension or hypotension;
disorders of hematopoietic function (sickle cell anemia, myeloma or leukemia);
recent myocardial infarction, chronic heart failure, or brain hemorrhage;
acute forms of liver and kidney damage;
hemophilia;
physical deformity of the penis (for example, Peyronie’s disease, cavernous fibrosis).
Children under 18 years of age and women should not take Sildigra 100, since sildenafil has not been studied in such groups of patients.
Sildenafil in clinical studies on animals did not show teratogenic effects on the fetus and did not affect the possibility of fertilization. Similar clinical studies have not been conducted in humans.
Measures taken in case of drug overdose
Exceeding the dosage of Sildigra 100 above the recommended doses does not increase the effectiveness of the drug. In contrast, an overdose increases the likelihood of adverse adverse reactions. With sildenafil intoxication, standard situational therapy is performed, aimed at removing the main adverse symptoms. Due to the significant binding of sildenafil to blood proteins, hemoperfusion or dialysis is ineffective for intoxication. The antidote is unknown.
Drug interaction
Tell your doctor about the medications you are taking, especially:
PDE-5 inhibitors (tadalafil, vardenafil or avanafil) or any other medications aimed at treating erectile dysfunction (yohimbine, alprostadil, etc);
medicines for the treatment of HIV / AIDS (saquinavir, ritonavir, atazanavir, indinavir, etc.);
medical preparations intended for the treatment of cardiovascular diseases, as well as some inhaled narcotic substances based on organic nitrates (nitroglycerin, amyl nitrite, butyl nitrite, and others);
antibiotics (clarithromycin, erythromycin, telithromycin, and others);
drugs-stimulants of guanylate cyclase (riociguat);
adrenoblockers (doxazosin, yohimbine hydrochloride, terazosin, prazosin, etc.);
antifungal substances (Itraconazole, ketoconazole).
Other medications, including vitamins, over-the-counter and prescription medications, and herbal products, may also interact with Sildigra 100. Contact your doctor for more information if you have any doubts about the background use of other medications listed here. Some groups of drugs listed above, when taken together with sildenafil, can be potentially life-threatening. For others, a significant reduction in the active dosage and personal supervision of the attending physician is required.
Interaction of Sildigra-100 with alcohol and certain food products
Grapefruit and grapefruit juice may affect sildenafil exposure. Try to avoid grapefruit products when using Sildigra 100.
Simultaneous intake of alcoholic beverages can lead to uncontrolled hypotension or to some undesirable effects (dizziness, nausea, severe headache, etc.).
Important information
Combined use of Sildigra 100 with certain medications can cause a cascade of undesirable and dangerous effects. Do not take Sildigra 100 if you are using substances for the treatment of angina based on nitrates, including some inhalation drugs — “poppers”, as well as drugs for the treatment of pulmonary hypertension — riociguat (Adempas).
Seek medical attention if the erection lasts more than 4 hours or is accompanied by pain. Priapism (or pathologically prolonged erection) can cause the origin of irreversible changes in the cavernous body of manhood.
Undesirable side effects
The main adverse reactions of Sildigra 100 occur due to an overdose of sildenafil or intolerance to the latter. They are quite rare and generally pass without consequences on their own after a few hours. Among them:
myalgia (pain in the lower back);
flu-like condition;
color perception disorder;
fever, tingling or redness of the chest and face;
dizziness;
nasal congestion;
headache.
Other adverse reactions are extremely rare and are mainly found in people who are prone to adverse reactions, who have health complications or combine taking medications (see Contraindications and Interactions) that are not compatible with sildenafil:
edema of the extremities;
signs of allergic reactions;
irregular breathing;
the first signs of a myocardial infarction are nausea, pain spreading to the jaw or shoulder, sweating;
painful erection lasting more than 4 hours;
tinnitus;
arrhythmia.
Sildenafil can reduce blood flow to the auditory or optic nerve, and can also cause loss or loss of vision or hearing. This has happened to a small number of people taking sildenafil. The majority of them were at risk or had other comorbidities: age over 50, diabetes, cardiovascular problems, pre-existing vision problems, hypercholesterolemia, Smoking, and hypertension. Whether sildenafil actually has a real causal relationship for vision loss is currently unknown.
Storage rules
Sildigra 100 should be stored away from children, in a dry and cool place, out of direct sunlight. The storage temperature should not exceed 30 °C. The end date of storage is indicated on the currency and must not exceed 36 months.